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. 2022 Jul 22;13(8):1329–1336. doi: 10.1021/acsmedchemlett.2c00249

Figure 5.

Figure 5

Graphical representation of the docked pose of the oxazino-quinoline derivative 26. The quinoline nitrogen gives a hydrogen bond with the imidazole ring of His220. Two additional hydrogen bonds are made by the oxygen and the nitrogen atom of the oxazine ring with the side chain OH groups of Thr224 and Thr243.