Table 5.
LCAT activity in HDL2 and HDL3 following 12-week intervention with either a low tomato diet, lycopene supplement, or high tomato diet.
| N | Baseline (470/390) |
WK 12 (470/390) |
Change at WK 12 (470/390) |
Pre vs. post P-value |
||
| HDL2 | Low tomato diet | 69 | 5.24 (0.26) | 5.28 (0.27) | 0.04 (−0.06, 0.14) | 0.919 |
| Lycopene supplement | 59 | 5.79 (0.28) | 5.85 (0.26) | 0.06 (−0.05, 0.16) | 0.161 | |
| High tomato diet | 63 | 5.15 (0.26) | 5.09 (0.26) | −0.06 (−0.16, 0.04) | 0.770 | |
| Between group P-value | 0.277 | 0.184 | 0.382 | |||
| HDL3 | Low tomato diet | 69 | 0.37 (0.02) | 0.37 (0.02) | −0.00 (−0.01, 0.01)a | 0.333 |
| Lycopene supplement | 59 | 0.37 (0.02) | 0.39 (0.02) | 0.01 (0.00, 0.02)b | 0.006 | |
| High tomato diet | 63 | 0.37 (0.02) | 0.38 (0.02) | 0.04 (−0.00, 0.01)a, b | 0.123 | |
| Between group P-value | 0.952 | 0.577 | 0.050 |
Results are expressed as mean (SEM) apart from change at week 12 which are presented as mean (95% CI). LCAT activity in HDL2 and HDL3 is expressed as 470:390 ratio and 470:390 ratio/mg protein, respectively. Differences in concentration changes at week 12 from baseline between groups were assessed by using one-factor ANOVA, with post-hoc LSD. Paired samples t-test was used to assess pre vs. post, with significance level set p ≤ 0.05. Values with different superscript letters are statistically significantly different (p < 0.05).