Table 6.
CETP activity in HDL2 and HDL3 following 12-week intervention with either a low tomato diet, lycopene supplement, or high tomato diet.
| N | Baseline | WK 12 | Change at WK 12 | Pre vs. post P-value |
||
| HDL2 | Low tomato diet | 69 | 1.07 (0.45) | 1.08 (0.44) | 0.01 (−0.01, 0.03)a | 0.382 |
| Lycopene supplement | 59 | 1.11 (0.43) | 1.04 (0.40) | −0.07 (−0.13, −0.01)b | 0.004 | |
| High tomato diet | 63 | 0.94 (0.45) | 0.93 (0.44) | −0.01 (−0.04, 0.01)a, b | 0.095 | |
| Between group P-value | 0.026 | 0.008 | 0.005 | |||
| HDL3 | Low tomato diet | 69 | 2.55 (2.04) | 2.93 (2.68) | 0.39 (0.09, 0.69)a | 0.714 |
| Lycopene supplement | 59 | 2.61 (2.90) | 1.84 (2.36) | −0.77 (−1.35, 0.20)b | <0.001 | |
| High tomato diet | 63 | 2.09 (1.82) | 1.84 (2.01) | −0.25 (−0.57, 0.08)b | <0.001 | |
| Between group P-value | 0.143 | 0.036 | 0.002 |
Results are expressed as mean (SEM) apart from change at week 12 which are presented as mean (95% CI). CETP activity in HDL2 and HDL3 is expressed as μmol/L and μmol/mg protein, respectively. Differences in concentration changes at week 12 from baseline between groups were assessed by using one-factor ANOVA, with post hoc LSD. Paired samples t-test was used to assess pre vs. post, with significance level set p ≤ .0.05. Values with different superscript letters are statistically significantly different (p < 0.05).