. 2022 Aug 15;18:312. doi: 10.1186/s12917-022-03400-7

Table 2.

Effect of low and high doses of metal nanocomposite on total leucocytic count (T.L.C) × 10³/ul and differential leucocytic count (D.L.C): monocytes (M), lymphocytes (L), heterophils (H), eosinophils (E) and basophils (B) (% of T.L.C), phagocytic activity of macrophage expressed as nitric oxide (NO) level and prothrombin time (PT) (Mean ± SE) n = 5

	G	T.L.C × 10³ /ul	M%	L%	H %	E%	B%	PhagocyticNO conc (μm)	PT (Second)
After treatment	1	13.87 ± 0.08^b	4.00 ± 0.00^b	55.60 ± 0.67^a	35.40 ± 0.60^a	5.00 ± 0.00^a	0.00 ± 0.00^a	82.80 ± 2.60^b	11.33 ± 0.2^ab
	2	12.67 ± 0.09^a	2.00 ± 0.00^a	54.40 ± 0.60^a	31.00 ± 0.80^b	9.60 ± 0.40^b	3.00 ± 0.00^b	65.20 ± 1.60^a	17.33 ± 0.40^e
	3	14.60 ± 0.06^c	5.80 ± 0.20^bc	54.60 ± 1.20^a	35.00 ± 1.40^a	4.00 ± 0.00^a	0.60 ± 0.00^c	89.20 ± 2.00^bc	11.00 ± 0.00^a
	4	15.73 ± 0.08 d	6.60 ± 0.20^c	55.60 ± 1.20^a	36.00 ± 0.60^a	1.60 ± 0.00^c	0.20 ± 0.00^a	108.20 ± 3.80^d	12.33 ± 0.20^b
	5	15.70 ± 0.12^d	7.00 ± 0.40^c	54.40 ± 0.60^a	37.60 ± 0.80^c	1.00 ± 0.00^c	0.00 ± 0.00^a	98.40 ± 2.80^cd	15.67 ± 0.20^d
	6	15.97 ± 0.08^d	7.60 ± 0.40^d	54.40 ± 0.33^a	38.00 ± 0.60^c	0.00 ± 0.00^d	0.00 ± 0.00^a	102.20 ± 3.20^d	14.33^c ± 0.40
At the end of the experiment	1	14.30 ± 0.21^c	4.60 ± 0.00^a	56.40 ± 0.58^a	35.00 ± 1.20^a	4.00 ± 0.00^a	0.00 ± 0.00^a	157.40 ± 3.80^d	12.33 ± 0.40^a
	2	11.07 ± 0.19^a	2.20 ± 0.00^b	54.60 ± 0.60^a	32.60 ± 0.80^b	8.60 ± 0.40^b	2.00 ± 0.00^b	96.40 ± 3.80^a	19.67 ± 0.40^c
	3	14.00 ± 0.15^bc	4.60 ± 0.20^a	56.00 ± 0.40^a	36.40 ± 0.40^a	2.00 ± 0.00^c	1.00 ± 0.00^c	123.60 ± 2.60^b	12.00 ± 0.00^a
	4	13.87 ± 0.18^bc	4.00 ± 0.00^a	55.60 ± 0.40^a	36.40 ± 0.60^a	4.00 ± 0.00^a	0.00 ± 0.00^a	129.80 ± 3.40^b	11.66 ± 0.40^a
	5	13.70 ± 0.12^b	3.40 ± 0.00^b	57.20 ± 0.60^b	35.40 ± 0.60^a	3.00 ± 0.00^a	1.00 ± 0.00^c	105.00 ± 2.80^a	15.33 ± 0.40^b
	6	14.03 ± 0.19^bc	4.00 ± 0.00^a	55.40 ± 0.60^a	36.00 ± 0.60^a	3.60 ± 0.00^a	1.00 ± 0.00^c	146.72 ± 1.80^c	14.00 ± 0.40^b

The various letters in the same column of the same period indicate statistically significant differences when (P < 0.05)

G1 = OTA free control, G2 = OTA fed positive control, G3 = OTA free (low dose), G4 = OTA free (high dose), G5 = OTA treated (low dose), G6 = OTA treated (high dose)