Table 1.
Baseline Characteristics | Overall (N= 110,655) |
Individuals with incident dementia (n=1439) |
Individuals without incident dementia (n=109,216) |
P value |
---|---|---|---|---|
Age, mean (SD), years | 56.5 (8.10) | 64.2 (4.88) | 56.4 (8.08) | <0.001 |
Gender, No. (%) | <0.001 | |||
Female | 59,469 (53.7) | 652 (45.3) | 58,817 (53.9) | |
Male | 51,186 (46.3) | 787 (54.7) | 50,399 (46.1) | |
Education level, No. (%) | <0.001 | |||
College or university degree | 35,744 (32.3) | 301 (20.9) | 35,443 (32.5) | |
Others | 74,911 (67.7) | 1138 (79.1) | 73,773 (67.5) | |
Systolic pressure, mean (SD), mmHg | 137 (18.5) | 143 (19.3) | 138 (18.5) | <0.001 |
Anti-hypertension treatment, No. (%) | <0.001 | |||
No | 100,148 (90.5) | 1211 (84.2) | 98,937 (90.6) | |
Yes | 10,507 (9.50) | 228 (15.8) | 10,279 (9.41) | |
Diabetes mellitus, No. (%) | <0.001 | |||
No | 103,950 (93.9) | 1207 (83.9) | 102,743 (94.1) | |
Yes | 6705 (6.06) | 232 (16.1) | 6473 (5.93) | |
Smoking status, No. (%) | <0.001 | |||
Never | 60,195 (54.7) | 666 (46.6) | 59,529 (54.8) | |
Former/current | 49,896 (45.3) | 762 (53.4) | 49,134 (45.2) | |
History of stroke, No. (%) | <0.001 | |||
No | 109,108 (98.6) | 1361 (94.6) | 107,747 (98.7) | |
Yes | 1547 (1.40) | 78 (5.42) | 1469 (1.35) | |
History of coronary heart disease, No. (%) | <0.001 | |||
No | 106,067 (95.9) | 1267 (88.1) | 104,800 (96.0) | |
Yes | 4588 (4.15) | 172 (12.0) | 4416 (4.04) | |
APOE ε4 carrier, No. (%) | <0.001 | |||
No | 83,454 (75.8) | 795 (55.6) | 82,649 (76.0) | |
Yes | 26,675 (24.2) | 635 (44.4) | 26,040 (24.0) |
SD standard deviation, No. number