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. 2021 Dec 24;37(2):230–244. doi: 10.46497/ArchRheumatol.2022.9086

Table 2. Clinical presentation of the included cases.

Reference Covid-19 test/results Clinical manifestations Comorbidities
Capone et al.,[12] All patients had evidence of SARS-CoV-2 infection (+ serology in 91%), Median of 4 days' fever, 97% had gastrointestinal symptoms & involvement of other organ system, 64% had symptoms fulfilling complete criteria of KD, 76% of patients complete KD criteria had shock (n=16). Myocardial dysfunction (58%) Overweight 2 6
Obesity 12 39
Whittaker et al.,[13] In total 78% had evidence of current or prior SARS-CoV-2, infection
PCR + in 26%,
SARS-CoV- IgG + 83%
All patients had fever 3-19 days, 10%
sore throat, 26% headache, vomiting
45%, abdominal pain 53%, diarrhea 52%, erythematous rash 52%, conjunctival injection 45%, respiratory symptoms 21%, lymphadenopathy 16%, swollen hands & feet 16%, mucous membrane changes and red cracked lips 29%
Asthma 3 5.2
Neuro-disability 1 1.7
Sickle-cell trait 1 1.7
Alopecia 1 1.7
Dufort et al.,[14] 96% were classified as having a confirmed case and 4% having a suspected case. 24% had a COVID-19 compatible illness a median of 21 days before hospitalization, 38% had exposure to a person with confirmed COVID-19 like illness, 22% had direct contact with a person who had a clinically compatible COVID-19 like illness PCR + 51%, Serology + 99% All presented with subjective fever or chills, 63% had fever on admission, 97% had tachycardia,78% had tachypnea, 32% hypotension 80% had GI symptoms, 60% had rash, 56% had conjunctival injection, 27% had mucosal changes, (Dermatologic 62%, mucucutaneous 61%), lower respiratory 40%, 61% had GI and either dermatologic or mucocutaneous symptoms Obesity 29 80.5
Pouletty et al.,[15] SARS-COVID was detected in 11 (96%). 31% (5 ) cases had documented recent contact with a quantitative PCR-positive individual PCR + 69%, Serology + 87% 44% cardiac involvement Fever (100%) Respiratory signs 2 (12%) Gastrointestinal signs 13 (81%) Neurological signs 9 (56%)Skin rash 13 (81%) Hands and feet erythema/oedema 11 (68%) Conjunctivitis 15 (94%) Dry cracked lips 14 (87%) Cervical lymphadenopathy 6 (37%) Hemodynamic failure 11 (69%) Complete Kawasaki disease: 10 (62%) Kawasaki disease shock syndrome 7 (44%) Overweight 4 25
Asthma 2 12.5
Belhadjer et al.,[16] 88% patients tested positive for SARS CoV-2 infection
PCR +40%
Serology + 86%
All children presented with fever and asthenia, gastrointestinal symptoms were prominent 80%, left ventricular ejection fraction less than 30% in one third Overweight 6 17
Asthma 3 8.5
Lupus 1 3
Toubiana et al.,[17] 90% had evidence of recent SARS-CoV-2 infection detected IgG antibodies against SARS-CoV-2. Two patients were negative.
PCR +38%
Serology +90%
52% presented with KD complete criteria syndrome, polymorphous skin rash 76%, 76% conjunctivitis injection 81% myocarditis. All had noticeable GI symptoms (abdominal pain, vomiting, and diarrhea) 95%, irritability 57%. 29% headache confusion, meningeal irritation. Pericardial effusion 48%. LVF 10%-57%. NA    
Verdoni et al.,[18] PCR +20% Serology +80% Five (50%) of 10 patients were diagnosed with incomplete Kawasaki disease, presenting with three or fewer clinical criteria associated with additional laboratory criteria (n=1) or an abnormal echocardiography (n=4). In these patients, echocardiography revealed left ventricular function depression, mitral valve regurgitation, and pericardial effusion; they also required inotropic support. Chest x-ray, done in all patients in group 2, was positive in five (50%) patients for minimal mono or bilateral infiltrates. Five (50%) of 10 patients in group 2 met the criteria for KDSS because of hypotension and clinical signs of hypoperfusion. Two (20%) patients had diarrhoea and meningeal signs, four (40%) had only diarrhoea, and two (20%) had only meningeal signs. NA