. 2022 Aug 11;37(1):2147–2157. doi: 10.1080/14756366.2022.2109024

Table 3.

Effects of compounds on ALP activity.

Compound	ALP activity (U/mg)
Normal	0.116 ± 0.003
DMSO	0.116 ± 0.003
AGEs	0.240 ± 0.003**
AGEs + DMSO	0.237 ± 0.002**
AGH	0.182 ± 0.003^ΔΔ
1	0.237 ± 0.004
2	0.229 ± 0.005^Δ
3	0.228 ± 0.003^ΔΔ
4	0.211 ± 0.005^ΔΔ
5	0.234 ± 0.005
6	0.229 ± 0.004^ΔΔ
7	0.214 ± 0.005^ΔΔ
8	0.239 ± 0.003^Δ
9	0.207 ± 0.005^ΔΔ
10	0.207 ± 0.006^ΔΔ
11	0.221 ± 0.002^ΔΔ
12	0.213 ± 0.003^ΔΔ
13	0.204 ± 0.004^ΔΔ
14	0.182 ± 0.003^ΔΔ
15	0.203 ± 0.003^ΔΔ
16	0.229 ± 0.003^ΔΔ
17	0.209 ± 0.003^ΔΔ
18	0.221 ± 0.002^ΔΔ
19	0.220 ± 0.003^ΔΔ
20	0.206 ± 0.003^ΔΔ
21	0.224 ± 0.002^ΔΔ
22	0.230 ± 0.003^ΔΔ
23	0.236 ± 0.003
24	0.228 ± 0.003^ΔΔ
25	0.207 ± 0.003^ΔΔ
26	0.234 ± 0.002
27	0.237 ± 0.004
28	0.206 ± 0.002^ΔΔ
29	0.230 ± 0.006^Δ
30	0.231 ± 0.003^ΔΔ
31	0.214 ± 0.003^ΔΔ
32	0.185 ± 0.002^ΔΔ
33	0.201 ± 0.005^ΔΔ
34	0.207 ± 0.003^ΔΔ
35	0.216 ± 0.016^Δ
36	0.223 ± 0.002^ΔΔ
37	0.205 ± 0.004^ΔΔ
38	0.235 ± 0.002
39	0.221 ± 0.003^ΔΔ
40	0.217 ± 0.003^ΔΔ
41	0.221 ± 0.003^ΔΔ
42	0.215 ± 0.004^ΔΔ
43	0.220 ± 0.003^ΔΔ
44	0.205 ± 0.003^ΔΔ

Effects of compounds on ALP activity. Most of the compounds can inhibit the increase of ALP induced by AGE, in vascular smooth muscle cells, and 14 and 32 have the best inhibitory effect on the ALP activity of calcified cells. ( $\bar{x} \pm s,$ n = 3, **P < 0.01, compared with normal control group at the same time. ^ΔP < 0.05, ^ΔΔP < 0.01, compared with AGEs group at the same time).