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. 2022 Aug 13;23(1):1–15. doi: 10.1080/15384047.2022.2108306

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© 2022 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Skeletal muscle inflammatory gene expression. a) Relative gene expression of macrophage surface proteins, cluster differentiation (CD) 68, EGF-like module-containing mucin-like hormone receptor-like 1 (EMR1; F4/80), Integrin, alpha X (Itgax; CD11c), and Mannose receptor C-type 1 (MRC1; CD206). b) Relative gene expression of inflammatory cytokines, Interleukin (IL) 6, IL-1β, tumor necrosis factor, and interferon (IFN) γ. c) Relative gene expression of anti-inflammatory cytokines IL-10 and IL-13. Gene values were normalized to vehicle treated controls and compared to five reference targets. Values are means ± SEM. Two-way ANOVA and LSD post hoc and multiple comparisons. #Indicates main effect of 5FU. %Indicates main effect of Obese. Different letters signify statistically significant differences with an interaction. Significance was set as p < .05.