Extended data Fig. 2. Cortical Pdgfrα⁺EdU⁺ cells and identity of Pdgfrα^- EDU⁺ cells.

a, Hippocampal density of Pdgfrα⁺ EdU⁺ cells per mm² (aCSF n=7, YM-CSF n=8; two-sided t-test; mean ± s.e.m.).

b, Hippocampal density of Pdgfrα⁺ cells per mm² (aCSF n=7, YM-CSF n=8; two-sided t-test; mean ± s.e.m.).

c, Location of region of interest in the cortex. Scale bar, 100μm.

d, Percentage of Pdgfrα⁺ EdU⁺ / Pdgfrα⁺ cells showing very low proliferation rates of OPCs in the cortex (n=6; two-sided t-test; mean ± s.e.m.).

e, Cortical density of Pdgfrα⁺ EdU⁺ cells per mm² (n=6; two-sided t-test; mean ± s.e.m.).

f, Cortical density of Pdgfrα⁺ cells per mm² (n=6; two-sided t-test; mean ± s.e.m.).

g, Percentage of Pdgfrα⁺ EdU⁺ / EdU⁺ in the hippocampus of aged mice infused with YM-CSF (n=3).

h, Example of IBA⁺ EdU⁺ cells in the hippocampus (n=3). Scale bar, 50μm. Insert, 10μm.

i, Example of GFAP⁺ EdU⁺ cells in the hippocampus (n=3). Scale bar, 50μm. Insert, 10μm.