Table 6.

Illustrative profiles of 5 participants with actualized cardiometabolic events. Participant profiles include demographic information, type of cardiometabolic disease, key physical measurements, clinical and genomic risk markers, and the top 5 important wearable-derived heart rate features (as per Shapley values).

Participant profiles		Participant
		A	B	C	D	E
Demographics
	Age (years)	54	57	56	55	61
	Gender	Male	Male	Male	Female	Male
	Wearable-derived resting heart rate	72.8	58.2	73.0	69.0	55.7
Clinical risk markers
	BMI (kg/m2)	28.05	18.79	21.27	22.95	25.95
	Blood pressure: SBPa/DBPb (mm Hg)	166/109	108/65	164/105	112/48	133/89
	Glucose (mmol/L)	6.8	4.8	7.4	5.3	5.3
	Total cholesterol (mmol/L)	5.27	6.63	6.60	5.05	4.45
	anyRISKoutof9	Truec	True	True	Falsed	False
High genomic risk
	Lipids abnormalities	True	True	False	False	False
	Blood pressure abnormalities	True	True	False	True	False
	Obesity	True	False	False	False	False
Actualized cardiometabolic events
	Cardiovascular disease	True	True	False	False	True
	Dyslipidemia	True	False	True	True	False
	Hypertension	True	False	False	False	False
Important features for prediction
	CO_f1ecac.sedentary	False	False	False	True	False
	FC_LocalSimple_mean3_stderr.sedentary	True	False	False	False	False
	SB_MotifThree_quantile_hh.sedentary	True	False	False	False	False
	SB_TransitionMatrix_3ac_sumdiagcov.sedentary	False	False	False	True	False
	CO_trev_1_num.sedentary	False	False	False	False	True
	CO_HistogramAMI_even_2_5.sedentary	False	False	True	False	False
	DN_OutlierInclude_p_001_mdrmd.sedentary	True	True	False	False	False
	CO_Embed2_Dist_tau_d_expfit_meandiff.sedentary	False	True	False	True	True
	DN_HistogramMode_10.sedentary	False	False	True	False	False
	DN_HistogramMode_5.sedentary	True	True	True	True	True
	Gender	True	True	True	False	True
	Age (years)	False	True	True	True	True

^aSBP: systolic blood pressure.

^bDBP: diastolic blood pressure.

^cTrue indicates true or that there is a presence of categorical variables.

^dFalse indicates false or absence of categorical variables.