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. 2022 Aug 15;17(8):2219–2228. doi: 10.1007/s11739-022-03052-3

Table 4.

Laboratory variables (at admission) associated with mortality by Cox regression

Variable Overall (n = 610) 1st wave (n = 397) 2nd wave (n = 213)
HR (CI95) p HR (CI95) p HR (CI95) p
Univariate
 CRP, mg/dL 1.064 (1.041–1.088) 3.49 × 10 − 8 1.046 (1.016–1.077) 0.003 1.059 (1.022–1.09) 0.002
 Lymphocytes, cells/mm3 0.9999 (0.9996–1.0002) 0.585 0.9997 (1.00026–1.00028) 0.345 1.0001 (0.9997–1.0006) 0.475
 Ferritin 0.9999 (0.9997–1.00001) 0.426 0.9998 (0.9996–1.00003) 0.099 0.9999 (0.9996–1.0003) 0.744
 D-Dimer 1.00003 (1.00002–1.00005) 1.11 × 10 − 5 1 (1.00002–1.00009) 0.003 1.00004 (1.00002–1.00005) 3.73 × 10 − 5
Multivariate
 CRP, mg/dL 1.057(1.030–1.084) 2.2 × 10 − 5 1.046 (1.0125–1.081) 0.007 1.043 (1.0006–1.089) 0.047
 D-Dimer 1.00002 (1.00001–1.00004) 9.84 × 10 − 4 1.00006 (1.00002–1.0001) 0002 1.00003 (1.00001–1.00005) 0.006

Upper panel: univariate analysis; lower panel: multivariate analysis

Significant p values (<0.05) are highlighted in bold