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. 2022 Aug 8;2022:4776243. doi: 10.1155/2022/4776243

Figure 9.

Figure 9

Melatonin prevents FA-induced acute kidney injury in mice. (a) Serum ALT. (b–d) BUN, serum creatinine (Scr), and Ccr level; the result shows that MT or Fer-1 could alleviate the kidney injury in FA-AKI. (e–h) Representative image of HE and PAS and tubular damage was scored semiquantitatively. (i) Real-time PCR of KIM-1 and IL-1β expression in FA-AKI model. Data represent the mean ± SEM for 6 mice in each group. ∗p < 0.05,  ∗∗p < 0.01, and∗∗∗p < 0.001 compared with the NC and NC+MT (20 mg/kg) groups. #p < 0.05,  ##p < 0.01, and###p < 0.001 compared with the folic acid- (FA-) treated group. Scale bar = 50 μm.