Figure 2.

The stimuli and identification of cellular senescence. Cellular senescence has two sides. On the one hand, cellular senescence can promote tissue remodeling and inhibit tumor development. On the other hand, accumulation of senescent cells can lead to a variety of aging-related diseases. Cellular senescence is caused by different stimuli, and the mechanism of cellular senescence is very complex. Therefore, the identification of senescent cells needs to be analyzed from different aspects.