Table 2.
The comparison of follow-up and baseline conditions of the study patients.
| Variable | Baseline | Follow-up | P |
|---|---|---|---|
| Years since HIV diagnosis | 0.1 (0.1, 0.2) | 3.3 (2.0, 5.7) | 0.000 |
| Years since HAART | — | 3.0 (1.8, 5.0) | — |
| Follow-up times | — | 15.0 (11.0, 22.0) | — |
| HAART options | 0.000 | ||
| 3TC + TDF + EFV | 153 (69.5%) | 118 (53.6%) | |
| 3TC + AZT + EFV | 30 (13.6%) | 27 (12.3%) | |
| NVP+3TC + AZT | 24 (10.9%) | 9 (4.1%) | |
| Others | 13 (5.9%) | 66 (30.0%) | |
| Co-trimoxazole | 0.000 | ||
| Yes | 156 (70.9%) | 195 (88.6%) | |
| No | 64 (29.1%) | 23 (10.5%) | |
| Missing | 0 (0.0%) | 2 (0.9%) | |
| Liver function impairment | 0.000 | ||
| Yes | 98 (44.1%) | 74 (33.3%) | |
| No | 124 (55.9%) | 125 (56.3%) | |
| Missing | 0 (0.0%) | 23 (10.4%) | |
| Leukopenia | 0.000 | ||
| Yes | 91 (41.4%) | 46 (20.9%) | |
| No | 129 (58.6%) | 150 (68.2%) | |
| Missing | 0 (0.0%) | 24 (10.9%) | |
| Anemia | 0.000 | ||
| Yes | 78 (35.5%) | 24 (10.9%) | |
| No | 144 (64.5%) | 174 (78.2%) | |
| Missing | 0 (0.0%) | 24 (10.9%) | |
| Viral load (copies/ml) | 97830.0 (35476.0, 254172.0) | 0.0 (0.0, 20.0) | 0.000 |
| CD4 counts (cells/μl) | 39.0 (20.3, 105.8) | 162.0 (128.3, 183.0) | 0.000 |
| WBC count (×109/L) | 4.2 (3.3, 5.1) | 4.8 (4.0, 5.7) | 0.000 |
| Plt count (×109/L) | 174.0 (135.8, 218.3) | 205.5 (170.3, 241.5) | 0.000 |
| Hb count (g/L) | 128.0 (113.0, 140.0) | 144.0 (130.0, 153.0) | 0.000 |
| Cr (μmol/L) | 71.8 (61.0, 82.5) | 70.0 (60.9, 82.0) | 0.393 |
| TG (mmol/L) | 1.4 (0.9, 1.9) | 1.5 (1.0, 2.4) | 0.027 |
| TC (mmol/L) | 3.8 (3.3, 4.3) | 4.4(3.8, 5.0) | 0.000 |
| FPG (mmol/L) | 5.5(4.9, 6.4) | 5.5 (5.2, 6.3) | 0.159 |
| AST (U/L) | 28.0 (21.0, 37.0) | 25.0 (20.0, 31.0) | 0.000 |
| ALT (U/L) | 23.5 (14.0, 41.0) | 20.0 (14.0, 28.5) | 0.002 |
| T.BIL (μmol/L) | 10.0 (7.5, 12.9) | 7.5 (5.6, 10.7) | 0.000 |
HAART, Highly active antiretroviral therapy; 3TC, Lamivudine; TDF, Tenofovir disoproxil; EFV, Efavirenz; AZT, Zidovudine; NVP, Nevirapine; WBC, White blood cell; Plt, Platelet; Hb, Hemoglobin; Cr, Creatinine; TG, Triglyceride; TC, Total cholesterol; FPG, Fasting plasma glucose; AST, Aspartate aminotransferase; ALT, Alanine aminotransferase; T.BIL, Total bilirubin. Data are presented as N (%) or Median (IQR). P values were determined by χ2 test or Wilcoxon signed rank test.