TABLE 2.
Base composition of the 5′ domain of selected IHF binding sites
| H′ DNA sequence | % A+T (no. in region/total no.)a in:
|
|
|---|---|---|
| +35 to +14 | +31 to +14 | |
| Class I | 57 (340/594) | 49 (236/486) |
| Class II | 58 (114/198) | 57 (93/162) |
| McClure consensusb | 76 (454/594) | 72 (352/486) |
| Wild-type H′ | 82 (18/22) | 78 (14/18) |
a
The percentage is the fraction of the sum of A · T base pairs in the designated region of each group of H′ sequences divided by the total number of bases and multiplied by 100.
b
The McClure consensus (7) was derived from 27 natural sequences aligned with the native H′ site.