Table 1.
Demographics of Derivation and Validation Cohorts.
| Derivation (N=16,611) |
Validation (N=19,512) |
p-value1 | |
|---|---|---|---|
| Kidney Function Pattern, n (%) | 0.38 | ||
| AKD | 754 (4.5) | 840 (4.3) | |
| AKD on CKD | 1225 (7.4) | 1506 (7.7) | |
| CKD | 4418 (27) | 5118 (26) | |
| Normal | 10214 (61) | 12048 (62) | |
| Age (Years), Median (IQR) | 56 (49 – 62) | 56 (49 – 61) | 0.87 |
| Female Sex, n (%) | 6421 (39) | 7648 (39) | 0.29 |
| Self-Identified Black, n (%) | 1297 (7.8) | 1391 (7.1) | 0.01 |
| Etiology of Cirrhosis, n (%) | 0.21 | ||
| Alcohol-Related | 3652 (22) | 4318 (22) | |
| Autoimmune-Related | 2305 (14) | 2649 (14) | |
| HCV | 5116 (31) | 6125 (31) | |
| NAFL | 4019 (24) | 4557 (23) | |
| Other | 1519 (9.1) | 1863 (10) | |
| MELDNa (Points), Median (IQR) | 18 (13 – 23) | 18 (13 – 23) | 0.81 |
| Ascites, n (%) | 6564 (40) | 7867 (40) | 0.12 |
| Hepatic Encephalopathy (HE), n (%) | 2201 (13) | 2702 (14) | 0.10 |
| Waitlist Outcome, n (%) | 0.43 | ||
| DDLT | 6355 (38) | 7524 (39) | |
| Death | 4806 (29) | 5710 (29) | |
| Waiting | 5450 (33) | 6278 (32) |
Acute Kidney Disease (AKD), Chronic Kidney Disease (CKD), interquartile range (IQR), Hepatitis C (HCV), Non-alcoholic Fatty Liver Disease (NAFL), Deceased Donor Liver Transplant (DDLT)
1
Pearson’s Chi-squared test; Wilcoxon rank sum test