Table-I.
Hematological parameters of rats during sub-acute toxicity studies.
| Parameters | Control | 125mg/kg | 250mg/kg | 500mg/kg |
|---|---|---|---|---|
| WBCs (10*3/ul) | 6.9 ± 0.071 | 6.5 ± 0.067 | 6.5 ± 0.45 | 6.4 ± 0.06 |
| RBCs (106/ul) | 6.3 ± 0.21 | 6.8 ± 0.21 | 6.5 ± 0.05 | 6.4 ± 0.08 |
| PLT (10*3/ul) | 652 ± 0.30 | 648± 0.34 | 655.7 ± 0.10 | 648.5± 0.16 |
| Hb (g/dl) | 12.7 ± 0.01 | 13.4 ± 0.05 | 12.7 ± 0.15 | 12.9 ± 0.05 |
| Neutrophils | 22.8± 0.01 | 22.7 ± 0.04 | 22.7 ± 0.01 | 23 ± 0.04 |
| Basophils | 0.125 ± 0.01 | 0.15 ± 0.03 | 0.175 ± 0.01 | 0.162 ± 0.01 |
| Lymphocytes | 73.2 ± 0.12 | 74.5 ± 0.19 | 73.5 ± 0.04 | 75 ± 0.05 |
| Monocytes | 0.82 ± 0.03 | 0.75 ± 0.01 | 0.78 ± 0.01 | 0.83 ± 0.02 |
| Eiosinophils | 2.2 ±0.001 | 2.1±0.04 | 2.1±0.05 | 2.1±0.02 |
There was no statistical difference between control group and PHF different dosages p≤0.05.