Table-II.
Biochemical parameters of rats during sub-acute toxicity studies.
| Parameters | Control | 150mg/kg | 250mg/kg | 500mg/kg |
|---|---|---|---|---|
| Blood Urea (mg/dl) | 44.8± 0.189 | 44.3 ± 0.78 | 44.3 ± 0.45 | 44 ± 0.12 |
| Creatinine (mg/dl) | 0.467 ± 0.007 | 0.49± 0.007 | 0.495 ± 0.007 | 0.49 ± 0.17 |
| Uric acid (mg/dl) | 3.34 ± 0.89 | 3.34 ± 0.160 | 3.35 ± 0.19 | 3.34 ±0.017 |
| Acid phosphatase (U/L) | 27.4 ± 0.071 | 29.3 ± 0.067 | 29.5 ± 0.45 | 29.7 ± 0.06 |
| Alkaline phaosphatase(U/L) | 63.1 ± 0.160 | 64.3 ± 0.067 | 64.2 ± 0.45 | 64 ± 0.189 |
| ALT (µl/ml) | 36.21 ± 0.21 | 35.23 ± 0.21 | 34.21± 0.05 | 35.21 ± 0.08 |
| AST (µl/ml) | 64.4 ± 0.30 | 36.17± 0.34 | 40.15 ± 0.10 | 39.34 ± 0.16 |
| Triglycerides (mg/dl) | 26.6 ± 0.30 | 26.3 ± 0.01 | 24.9 ± 0.10 | 27.8 ± 0.30 |
| HDL (mg/dl) | 25.5 ± 0.189 | 24.7± 0.05 | 24.3 ± 0.5 | 24.1 ± 0.30 |
| LDL (mg/dl) | 10.3 ± 0.05 | 10.3 ± 0.4 | 10.6 ± 0.30 | 10.2 ± 0.189 |
There was no statistical difference between control group and PHF different dosages p≤0.05.