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. Author manuscript; available in PMC: 2023 Aug 1.
Published in final edited form as: J Allergy Clin Immunol. 2022 Mar 15;150(2):373–384. doi: 10.1016/j.jaci.2022.03.002

Figure 1. Cell composition of EC sensitized mouse skin by scRNA-Seq.

Figure 1.

A. t-Distributed stochastic neighbor embedding (tSNE) plot for 14,211 high quality single cell transcriptomes from mouse skin EC sensitized with saline (n=3) and OVA (n=3), revealing 13 different cell populations. B. Fractions of cell populations identified in EC sensitized skin with saline (Sal) and OVA. C. Dot plot displaying top expressed genes in each cell population compared to the other cell populations identified in EC sensitized skin. D. Boxplot of the distribution of seven selected cell populations in mouse skin EC sensitized with OVA or saline. *p< 0.05, ** p< 0.005 and *** p< 0.001.