TABLE 1.
Baseline characteristics, mean (SD) or %
| Overall N= 534 |
Seated |
Supine |
|||
|---|---|---|---|---|---|
| No OH, N= 513 | OH, N= 21 | No OH, N= 425 | OH, N= 109 | ||
| Age, year | 76.3 (5.3) | 76.2 (5.3) | 78.4 (6.3) | 76.2 (5.2) | 76.8 (5.7) |
| Men, % | 58.1 | 58.9 | 38.1 | 57.6 | 59.6 |
| Black, % | 18.0 | 17.3 | 33.3 | 17.4 | 20.2 |
| Baseline seated blood pressure, mmHg | |||||
| Systolic | 129.8 (18.6)a | 129.3 (18.5)a | 140.3 (19.9) | 129.6 (18.5)a | 130.3 (19.2) |
| Diastolic | 67.9 (10.7)a | 67.8 (10.8)a | 70.2 (7.8) | 68.0 (10.7)a | 67.5 (10.7) |
| Body mass index, kg/m2 | 30.2 (5.3) | 30.3 (5.3) | 29.4 (6.0) | 30.3 (5.3) | 29.8 (5.3) |
| History of cardiovascular disease, % | 28.8 | 28.5 | 38.1 | 28.7 | 29.4 |
| History of diabetes, % | 26.8 | 26.5 | 33.3 | 26.6 | 27.5 |
| History of Parkinson’s disease, % | 1.5 | 1.4 | 4.8 | 1.2 | 2.8 |
| History of high blood pressure or hypertension, % | 62.0 | 61.0 | 85.7 | 62.8 | 58.7 |
| Antidepressant use, % | 17.0 | 17.0 | 19.0 | 15.8 | 22.0 |
| Parkinson’s disease medication use, % | 0.6 | 0.7 | 0.0 | 0.0 | 0.0 |
| Antipsychotic use, % | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| ACE inhibitor/ARB use, % | 47.4 | 46.4 | 71.4 | 48.7 | 42.2 |
| Beta blocker use, % | 29.6 | 29.0 | 42.9 | 30.6 | 25.7 |
| Calcium channel blocker use, % | 22.3 | 22.2 | 23.8 | 21.9 | 23.9 |
| Diuretic use, % | 19.7 | 20.1 | 9.5 | 20.2 | 17.4 |
| Central alpha agonist use, % | 0.7 | 0.8 | 0.0 | 0.9 | 0.0 |
| Alpha blocker use, % | 8.6 | 8.4 | 14.3 | 6.8 | 15.6 |
| Fall in the past year, % | 62.9 | 62.4 | 76.2 | 62.1 | 66.1 |
Abbreviations: ACE, angiotensin-converting enzyme; ARB, angiotensin II receptor blocker; OH, orthostatic hypotension; SD, standard deviation.
a
There were only 533 with blood pressure measured in the seated position at baseline. This corresponds to 512 without orthostatic hypotension with the seated