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. Author manuscript; available in PMC: 2023 Aug 1.
Published in final edited form as: Mol Neurobiol. 2022 Jun 7;59(8):5104–5120. doi: 10.1007/s12035-022-02905-4

Figure 1. Expression patterns of WDR5 in the developing cortex.

Figure 1.

(A) Expression of WDR5 in embryonic and postnatal mouse brains. Immunostaining for WDR5 showed that the protein was broadly expressed in the embryonic mouse brains. In postnatal mouse brains, WDR5 was highly expressed in the upper-layer cortical plate. Scale bar, 50μm, 150μm. CP, Cortical plate; IZ, intermediate zone, VZ, ventricular zone, SVZ, subventricular zone; II-VI, cortical layers II-VI. (B) WDR5 immunostaining in NeuN-positive cells in postnatal mouse brains. WDR5 was highly expressed in upper-layer cortical neurons at P14, suggesting roles for WDR5 in neuron differentiation. Scale bar, 25μm. (C) WDR5 immunostaining in MAP2-positive neurons in culture. Scale bar, 10μm.