Table 1.
Within Trial Resource Use (Overall and Stratified by Follow up period)
| Resource Use* | Catheter Ablation (N=1108) |
Drug Therapy (N=1096) |
Difference (ablation – drug) |
|---|---|---|---|
| Total Within Trial | |||
| Hospitalizations | 2.59 (2.25) | 2.16 (2.27) | 0.43 |
| First Ablation | 0.88 (0.33) | 0.23 (0.42) | 0.65 |
| Repeat / Redo Ablation | 0.20 (0.49) | 0.07 (0.31) | 0.13 |
| Non-Ablation Arrhythmia Management | 0.55 (1.01) | 0.95 (1.17) | −0.40 |
| Heart Failure | 0.09 (0.45) | 0.08 (0.41) | 0.01 |
| Other Cardiovascular | 0.24 (0.69) | 0.24 (0.64) | 0.00 |
| Non-Cardiovascular | 0.63 (1.18) | 0.58 (1.16) | 0.05 |
| Time in Hospital, days | 10.56 (16.55) | 8.98 (15.10) | 1.58 |
| ICU / CCU | 0.83 (3.15) | 0.84 (3.46) | −0.01 |
| Non ICU / CCU | 9.73 (15.70) | 8.14 (14.34) | 1.59 |
|
| |||
| Within First 90 days by Intention to Treat | |||
| Hospitalizations | 1.06 (0.68) | 0.63 (0.73) | 0.43 |
| First Ablation | 0.78 (0.41) | 0.03 (0.17) | 0.75 |
| Repeat / Redo Ablation | 0.01 (0.09) | 0.00 (0.00) | 0.01 |
| Non-Ablation Arrhythmia Management | 0.15 (0.41) | 0.51 (0.62) | −0.36 |
| Heart Failure | 0.02 (0.14) | 0.02 (0.14) | 0.00 |
| Other Cardiovascular | 0.04 (0.21) | 0.03 (0.22) | 0.01 |
| Non-Cardiovascular | 0.06 (0.24) | 0.04 (0.23) | 0.02 |
| Time in Hospital, days | 3.77 (5.15) | 2.59 (4.56) | 1.18 |
| ICU / CCU | 0.25 (1.01) | 0.29 (1.57) | −0.04 |
| Non-ICU / CCU | 3.52 (4.99) | 2.30 (4.18) | 1.22 |
|
| |||
| Between 90 to 365 days by Intention to Treat | |||
| Hospitalizations | 0.45 (0.83) | 0.45 (0.83) | 0.00 |
| First Ablation | 0.08 (0.27) | 0.09 (0.29) | −0.01 |
| Repeat / Redo Ablation | 0.07 (0.27) | 0.01 (0.11) | 0.06 |
| Non-Ablation Arrhythmia Management | 0.12 (0.41) | 0.15 (0.45) | −0.03 |
| Heart Failure | 0.02 (0.15) | 0.02 (0.22) | 0.00 |
| Other Cardiovascular | 0.05 (0.23) | 0.07 (0.33) | −0.02 |
| Non-Cardiovascular | 0.11 (0.36) | 0.11 (0.42) | 0.00 |
| Time in Hospital, days | 1.73 (5.86) | 1.66 (4.29) | 0.07 |
| ICU / CCU | 0.17 (2.10) | 0.18 (1.22) | −0.01 |
| Non-ICU / CCU | 1.57 (4.90) | 1.48 (3.94) | 0.09 |
|
| |||
| Between 365 days to 5-years by Intention to Treat | |||
| Hospitalizations | 1.09 (1.77) | 1.08 (1.67) | 0.01 |
| First Ablation | 0.02 (0.13) | 0.12 (0.32) | −0.10 |
| Repeat/Redo Ablation | 0.13 (0.37) | 0.06 (0.28) | 0.07 |
| Non-Ablation Arrhythmia Management | 0.27 (0.68) | 0.29 (0.74) | −0.02 |
| Heart Failure | 0.06 (0.36) | 0.04 (0.26) | 0.02 |
| Other Cardiovascular | 0.15 (0.60) | 0.14 (0.45) | 0.01 |
| Non-Cardiovascular | 0.46 (1.05) | 0.43 (0.95) | 0.03 |
| Time in Hospital, days | 5.06 (12.26) | 4.73 (11.90) | 0.33 |
| ICU / CCU | 0.41 (1.98) | 0.37 (2.51) | 0.04 |
| Non-ICU / CCU | 4.65 (11.74) | 4.36 (11.21) | 0.29 |
*
Medical resource use is reported as mean (standard deviation) from observed data through 5 years of CABANA trial follow up. This table excludes ablations that did not have a corresponding hospitalization documented on the study case report form. Abbreviations: CCU – coronary care unit; ICU – intensive care unit.