TABLE 1.
Selected data from monozygotic twin pairs discordant for leisure time physical activity habits pooled from TWINACTIVE and FITFATTWIN studies
| Less active co‐twins (N = 17) | More active co‐twins (N = 17) | Intrapair difference Mean (95% CI) | |
|---|---|---|---|
| Mean ± SD | |||
| VO2peak, ml/kg/min | 33.0 ± 6.6 | 38.6 ± 7.6 | 5.6 (3.3–8.0) |
| Past 12‐month LTPA, LTMET‐hours/day | 2.0 ± 1.8 | 6.1 ± 3.7 | 4.1 (2.5–5.6) |
| Waist circumference, cm | 92.3 ± 9.0 | 88.4 ± 7.8 | −3.9 (−6.9 to −0.8) |
| Fat percent, % | 22.6 ± 6.0 | 19.7 ± 4.7 | −3.0 (−5.6 to −0.6) |
| Visceral adipose tissue area, cm2 | 144 ± 54 | 107 ± 55 | −37 (−61 to −13) |
| Liver fat index, MRI signal intensity | 15.1 ± 16.6 | 6.8 ± 5.9 | −8.3 (−15.4 to −1.1) |
| ApoB:ApoA1 ratio | 0.61 ± 0.13 | 0.53 ± 0.03 | −0.08 (−0.13 to −0.02) |
| HDL cholesterol, mmol/L | 1.43 ± 0.10 | 1.54 ± 0.11 | 0.11 (0.01–0.22) |
| HDL2 cholesterol, mmol/L | 0.93 ± 0.35 | 1.05 ± 0.42 | 0.12 (0.02–0.22) |
| HDL diameter, nm | 9.72 ± 0.23 | 9.83 ± 0.24 | 0.11 (0.05–0.16) |
| Very large HDL particles, μmol/L | 0.21 ± 0.11 | 0.27 ± 0.16 | 0.07 (0.02–0.11) |
| Large HDL particles, μmol/L | 0.80 ± 0.43 | 0.98 ± 0.50 | 0.17 (0.08–0.27) |
| Medium HDL particles, μmol/L | 1.82 ± 0.47 | 1.82 ± 0.43 | −0.00 (−0.13 to 0.12) |
| Small HDL particles, μmol/L | 4.64 ± 0.36 | 4.55 ± 0.39 | −0.09 (−0.25 to 0.06) |
Abbreviations: ApoA1, apolipoprotein A1; ApoB, apolipoprotein B; CI, confidence interval; HDL, high density lipoprotein; LTMET‐hours/day, leisure‐time metabolic equivalent for physical activity during leisure‐time and the commute to and from work indicating daily leisure‐time physical activity volume; MRI, magnetic resonance imaging.