Table 1.

Subunit interactions in the VSV nucleocapsid

Intra-layer N contacts		IAa (Å2)
Lateral intra-layer contacts
Interface 1	Single stranded RNA bound to N subunit	1055
Interface 2	Ni N-terminal arm interacts with Ni-1 C-terminal lobe and with Ni-2 extended loop	793, 354
Interface 3	Ni extended loop interacts with Ni+1 C-terminal lobe and with Ni+2 N-terminal arm	683, 354
Interface 4	Ni N-terminal lobe interacts with Ni+1 N-terminal lobe	442
Interface 5	Ni C-terminal lobe interacts with Ni+1 C-terminal lobe	207
Axial intra-layer contacts
Interface A	Ni subunit interacts with Ni+39 subunit	94
Interface B	Ni subunit interacts with Ni+38 subunit	18

Intra-layer M1 contacts		IA (Å2)
Lateral intra-layer contacts
Interface 6	M1i globular domain interacts with M1i+1 globular domain	65
Axial intra-layer contacts
Interface C	M1i self-association motif interacts with M1i-38 globular domain	400
Interface D	M1i globular domain interacts with M1i+39 globular domain	78

Intra-layer M2 contacts		IA (Å2)
Axial intra-layer contacts
Interface E	M2i globular domain interacts with M2i+38 globular domain	49

Inter-layer N-M1 contacts		IA (Å2)
Radial inter-layer contacts
Interface i	Ni C-terminal lobe interacts with M1i globular domain	345
Interface ii	Ni C-terminal lobe interacts with M1i-38 globular domain	310
Interface iii	Ni C-terminal lobe interacts with M1i+1 globular domain	117

Inter-layer M1-M2 contacts		IA (Å2)
Radial inter-layer contacts
Interface iv	M1i globular domain interacts with M2i globular domain	600
Interface v	M1i globular domain interacts with M2i+1 globular domain	430

^aIA: interface area (buried accessible surface area upon interface formation).