Table 3.
Associations between sociodemographic characteristics and fertility preservation use among AYA women with cancer in North Carolina, 2004-2015a
| Model 1: age at diagnosis |
n, FP | n, no FP | Unadjusted OR (95% CI) |
Adjusted ORb (95% CI) |
|---|---|---|---|---|
| 15-24 years | 96 | 480 | 2.61 (1.27, 5.36) | 3.17 (1.31, 7.70) |
| 25-29 years | 6.15 (3.53, 10.73) | 6.27 (3.35, 11.73) | ||
| 30-34 years | 2.73 (1.55, 4.82) | 2.53 (1.39, 4.62) | ||
| 35-39 years | 1. | 1. | ||
| Model 2: race and ethnicity |
n, FP | n, no FP | Unadjusted PR (95% CI) |
Adjusted PR (95% CI) |
| Hispanic | 96 | 7827 | 0.52 (0.19, 1.43) | No adjustment set |
| Non-Hispanic Black | 0.44 (0.24, 0.79) | |||
| Non-Hispanic all other races | 0.85 (0.31, 2.30) | |||
| Non-Hispanic White | 1. | |||
| Model 3: parity at diagnosis |
n, FP | n, no FP | Unadjusted PR (95% CI) |
Adjusted PRc (95% CI) |
| Nulliparous | 92 | 7762 | 1. | 1. |
| Parous | 0.30 (0.17, 0.52) | 0.24 (0.13, 0.45) | ||
| Model 4: rurality | n, FP | n, no FP | Unadjusted PR (95% CI) |
Adjusted PRd (95% CI) |
| Non-urban | 93 | 7801 | 0.12 (0.04, 0.38) | 0.12 (0.04, 0.37) |
| Urban | 1. | 1. | ||
| Model 5: education (census tract: % with ≥ Bachelor’s degree) |
n, FP | n, no FP | Unadjusted PR (95% CI) |
Adjusted PRe (95% CI) |
| Tertile 1 (lowest) | 93 | 7836 | 0.12 (0.06, 0.25) | 0.16 (0.08, 0.35) |
| Tertile 2 | 0.41 (0.26, 0.64) | 0.47 (0.29, 0.74) | ||
| Tertile 3 (highest) | 1. | 1. | ||
| Model 6: income (census tract: median household income) |
n, FP | n, no FP | Unadjusted PR (95% CI) |
Adjusted PRe (95% CI) |
| Tertile 1 (lowest) | 93 | 7831 | 0.23 (0.12, 0.41) | 0.31 (0.17, 0.58) |
| Tertile 2 | 0.56 (0.36, 0.88) | 0.64 (0.41, 1.01) | ||
| Tertile 3 (highest) | 1. | 1. | ||
| Model 7: Yost SES index (census tract) |
n, FP | n, no FP | Unadjusted PR (95% CI) |
Adjusted PRf (95% CI) |
| Quintile 1 – Quintile 3 (lowest) | 92 | 7632 | 0.28 (0.18, 0.44) | 0.39 (0.25, 0.61) |
| Quintile 4 – Quintile 5 (highest) | 1. | 1. |
Abbreviations: CI, confidence interval; FP, fertility preservation; PR, prevalence ratio; SES, socioeconomic status.
a
Adjusted estimates exclude women who were missing data for any model covariates. Sample sizes by FP use reflect the number of women included in the adjusted model.
b
Women who used FP were matched 1:5 to women who did not use FP on cancer type.
c
Adjusted for age at diagnosis and Yost SES index.
d
Adjusted for race and ethnicity.
e
Adjusted for rurality.
f
Adjusted for race and ethnicity and rurality.