Table 1. Patient demographics.
| Parameter | Lung Controls | COPD Patients | IPF Patients | Overall p-value |
|---|---|---|---|---|
| Subjects, n # | 9# | 10# | 6# | |
| Gender, male/female# | 3/6# | 6/4# | 5/1# | |
| Age, years | 74 (64–78) # | 62 (59–64) | 60 (53–66) † | 0.0334 |
| Height, m | 1.6 (1.5–1.8) | 1.8 (1.6–1.8) | 1.8 (1.6–1.8) | 0.1347 |
| Body mass index, kg/m2 | 32.7 (25.7–60.2) | 30.1 (25.7–35.4) | 32.5 (29.2–37.0) | 0.2727 |
| Smoking status, never/ex/current | 2/6/1 | 0/10/0 | 4/2/0 | |
| FEV1, L | 1.8 (1.7–2.4) | 0.8 (0.6–0.8) † | 2.0 (1.5–2.5) | 0.0002 |
| FEV1/(F)VC, % | 82 (66–121) | 78 (71–88) † | 67 (65–70) | <0.0001 |
| FEV1, % of predicted | 85 (72–95) | 22 (18–29) † | 67 (44–76) | 0.0003 |
| DLCO | 88 (65–110) | 36 (28–43) † | 29 (24–50) § | <0.0001 |
| Corticosteroids (yes/no/unknown) | 0/9/0 | 9/0/1 | 4/2/0 |
Values are median (range) or n. Statistical analysis was performed using Kruskal–Wallis nonparametric test followed by Dunn’s multiple comparison post-test. Chronic obstructive pulmonary disease (COPD); Idiopathic pulmonary fibrosis (IPF); FEV1: forced expiratory volume in 1 s; (F)VC: (forced) vital capacity; diffusing capacity of the lungs for carbon monoxide (DLCO). #The mean value of the study group is 68 years. †p = 0.0334 vs. Lung Controls. †p = 0.0002 vs. Lung Controls. †p < 0.0001 vs. Lung Controls. †p = 0.0003 vs. Lung Controls. §p < 0.0001 vs. Lung Controls.