Table 2. Correlations between mast cell CPA3 and lung function parameters.
| Mast Cell CPA3 | Lung Compartments | FEV1 | FEV1% | FEV1/VC | DLCO% |
|---|---|---|---|---|---|
| CPA3 mRNA | Small Airways |
r = −0.4168 p = 0.0602 |
r = −0.4508
p = 0.0403 |
r = −0.3449 p = 0.1257 |
r = −0.3681 p = 0.1459 |
| Pulmonary Vessels |
r = −0.5092
p = 0.0155 |
r = −0.513
p = 0.0146 |
r = −0.5369
p = 0.0100 |
r = −0.2097 p = 0.4036 |
|
| Alveolar Region |
r = 0.06733 p = 0.7659 |
r = −0.1672 p = 0.4570 |
r = 0.06337 p = 0.7794 |
r = −0.3988 p = 0.1012 |
|
| CPA3 Protein | Small Airways |
r = 0.2748 p = 0.2280 |
r = 0.2762 p = 0.2256 |
r = 0.2227 p = 0.3320 |
r = −0.2038 p = 0.4293 |
| Pulmonary Vessels |
r = 0.4932
p = 0.0197 |
r = 0.6736
p = 0.0006 |
r = 0.6389
p = 0.0014 |
r = 0.1509 p = 0.5500 |
|
| Alveolar Region |
r = 0.2691 p = 0.2259 |
r = 0.325 p = 0.1401 |
r = 0.2632 p = 0.2367 |
r = −0.2749 p = 0.2695 |
|
| CPA3 Protein/mRNA | Small Airways |
r = 0.5766
p = 0.0062 |
r = 0.666
p = 0.0010 |
r = 0.4727
p = 0.0305 |
r = 0.1694 p = 0.5123 |
| Pulmonary Vessels |
r = 0.5645
p = 0.0062 |
r = 0.7234
p = 0.0001 |
r = 0.6786
p = 0.0005 |
r = 0.1292 p = 0.6094 |
|
| Alveolar Region | 0.2765 p = 0.2130 |
0.4346
p = 0.0433 |
0.2218 p = 0.3211 |
−0.05685 p = 0.8227 |
Spearman r non-parametric correlation analysis was performed using Prism (Version 9.3.1). r = correlation coefficient, p = p value. Statistically confirmed correlations (i.e., p < 0.05) are marked in bold. FEV1: forced expiratory volume in 1 s; VC: vital capacity; diffusing capacity of the lungs for carbon monoxide (DLCO).