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. 2022 Aug 2;12:816198. doi: 10.3389/fonc.2022.816198

Table 1 Clinical characteristics.

Items HCC patients (N = 101)
Demographic characteristics
Age (years), mean ± SD 56.8 ± 11.2
Gender, No. (%)
 Female 12 (11.9)
 Male 89 (88.1)
Disease characteristics
HBV, No. (%) 75 (74.3)
ECOG PS score, No. (%)
 0 26 (25.7)
 1 74 (73.3)
 2 1 (1.0)
Child–Pugh class, No. (%)
 A 72 (71.3)
 B 29 (28.7)
Extrahepatic metastasis, No. (%) 56 (55.4)
Vascular invasion, No. (%) 42 (41.6)
BCLC stage, No. (%)
 B 29 (28.7)
 C 72 (71.3)
CNLC stage, No. (%)
 Ib 1 (1.0)
 IIa 1 (1.0)
 IIb 16 (15.8)
 IIIa 26 (25.8)
 IIIb 56 (55.4)
 UK 1 (1.0)
AFP (ng/ml), No. (%)
 <400 57 (56.4)
 ≥400 39 (38.6)
 UK 5 (5.0)
Treatment history
Hepatectomy, No. (%) 27 (26.7)
Times of previous TACE, No. (%)
 0 29 (28.7)
 1 32 (31.7)
 2 16 (15.8)
 3 7 (6.9)
 >3 17 (16.8)
Refectory to TACE in patients with TACE treatment history, No. (%)
 No 26 (25.7)
 Yes 31 (30.7)
Previous treatment lines, No. (%)
 First-line 82 (81.2)
 Second-line 17 (16.8)
 > Second-line 2 (2.0)
Treatment in the study
Times of TACE, No. (%)
 ≤3 88 (87.1)
 >3 13 (12.9)
Timing of camrelizumab administration, No. (%)
 Before TACE 9 (8.9)
 After TACE 92 (91.1)
Treatment cycle of camrelizumab
 Q2W 2 (2.0)
 Q3W 99 (98.0)
Cycles of camrelizumab, No. (%)
 ≤2 12 (11.9)
 3–4 33 (32.7)
 >4 56 (55.4)
Interval between TACE and camrelizumab administration, No. (%)
 Within 7 days 84 (83.2)
 Within 8 to 14 days 9 (8.9)
 Within 15 to 28 days 8 (7.9)
Treatment regimen, No. (%)
 Monotherapy of camrelizumab 53 (52.5)
 Combination therapy with TKI 48 (47.5)
 Apatinib 27 (26.7)
 Lenvatinib 10 (9.9)
 Sorafenib 4 (4.0)
 Anlotinib 4 (4.0)
 Regorafenib 3 (3.0)

HCC, hepatocellular carcinoma; SD, standard deviation; HBV, hepatitis B virus; ECOG PS, Eastern Cooperative Oncology Group Performance Status; BCLC, Barcelona Clinic Liver Cancer; CNLC, China liver cancer; UK, unknown; AFP, alpha-fetoprotein; TACE, transarterial chemoembolization; Q2W, every 2 weeks; Q3W, every 3 weeks; TKI, tyrosine kinase inhibitors.