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. 2022 Aug 2;12:816198. doi: 10.3389/fonc.2022.816198

Table 4.

Factors affecting PFS and OS by multivariate Cox’s proportional hazards regression analysis.

Items PFS OS
P-value HR (95% CI) P-value HR (95% CI)
Vascular invasion (yes vs. no) 0.147 1.775 (0.818–3.852) 0.001 9.030 (2.355–34.629)
Higher CNLC stage 0.950 1.016 (0.619–1.667) 0.384 1.478 (0.613–3.560)
AFP (≥400 ng/ml vs. <400 ng/ml) 0.274 0.638 (0.285–1.427) 0.079 2.636 (0.895–7.762)
More times of previous TACE 0.389 0.851 (0.590–1.228) 0.018 1.618 (1.088–2.407)
More times of TACE 0.377 0.645 (0.243–1.708) 0.107 0.233 (0.040–1.368)
More cycles of camrelizumab 0.002 0.415 (0.240–0.718) 0.070 0.484 (0.220–1.062)
Longer interval between TACE and camrelizumab administration 0.032 1.873 (1.056–3.322) 0.097 1.811 (0.898–3.654)

PFS, progression-free survival; OS, overall survival; HR, hazard ratio; CI, confidence interval; CNLC, China liver cancer; AFP, alpha-fetoprotein; TACE, transarterial chemoembolization. The bold values indicate the comparison with statistical significance.