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. 2022 Aug 10;12(8):e057852. doi: 10.1136/bmjopen-2021-057852

Table 2.

Multivariate analysis of factors associated with positive SARS-CoV-2 nucleic tests (N=15 690)

Univariate analysis, OR (95% CI) Final model with fully adjusted OR (95% CI)* P value
Sex
 Male Reference Reference 0.18
 Female 0.84 (0.59 to 1.21) 0.78 (0.54 to 1.12)
Age
1.00 (1.00 to 1.02) 1.00 (0.99 to 1.01) 0.27
7-day average incident COVID-19 cases
 0–1.99 daily cases per 100 000 population Reference Reference <0.001
 2–7.99 daily cases per 100 000 population 1.42 (0.91 to 2.22) 1.47 (0.94 to 2.31)
 ≥8 daily cases per 100 000 population 2.99 (1.95 to 4.59) 3.17 (2.05 to 4.89)
COVID-19-compatible symptoms present
 No Reference Reference 0.08
 Yes 2.08 (1.71 to 3.71) 1.65 (0.90 to 3.00)
Self-reported fever or temperature ≥37.5°C
 No Reference Reference <0.001
 Yes 2.72 (1.89 to 3.90) 2.53 (1.74 to 3.67)
Diarrhoea present
 No Reference Reference 0.11
 Yes 1.74 (1.04 to 2.92) 1.57 (0.93 to 2.67)
Healthcare worker
 No Reference Reference 0.06
 Yes 5.62 (1.35 to 23.43) 4.67 (1.05 to 20.54)
Household contact or caregiver
 No Reference Reference <0.001
 Yes 9.48 (5.01 to 17.96) 7.74 (3.98 to 15.04)
Institutional exposure
 No Reference Reference <0.001
 Yes 3.46 (2.17 to 5.52) 3.39 (2.10 to 5.47)
Dysgeusia or anosmia present
 No Reference
 Yes 3.21 (0.43 to 23.52)
Dyspnoea present
 No Reference
 Yes 1.16 (0.80 to 1.70)
Nausea or vomiting present
 No Reference
 Yes 0.81 (0.51 to 1.29)

*Final model determined by including variables with p<0.20 from univariable analyses and using the Akaike’s information criterion to determine additional variables to exclude from the final model. Variables adjusted for all other variables present in the final model.