Table 2.

Antimicrobials prescribed by Belgian dentists in the ambulatory setting from 2010 to 2016, calculated in DDD (top), in DID (middle) and in DDD per prescriber (bottom)

Antimicrobial group	2010	2011	2012	2013	2014	2015	2016
	DDD (×1,000)
Antibacterials for systemic use (J01)	5983.4	6130.4	6218.2	6455.0	6420.1	6597.8	6652.8
Antiprotozoals (P01AB)	43.2	45.4	47.8	50.9	54.6	58.9	59.3

Antimicrobial product	DID
Amoxicillin (J01CA04)	0.702	0.717	0.732	0.762	0.770	0.792	0.789
Amoxicillin + enzyme inhibitor (J01CR02)	0.561	0.570	0.565	0.595	0.587	0.609	0.620
Ratio J01CA04/J01CR02*	1.251	1.258	1.296	1.281	1.312	1.300	1.273
Clindamycin (J01FF01)	0.074	0.074	0.078	0.079	0.076	0.076	0.075
Clarithromycin (J01FA09)	0.058	0.055	0.049	0.045	0.043	0.040	0.039
Doxycycline (J01AA02)	0.050	0.049	0.045	0.042	0.036	0.034	0.031
Azithromycin (J01FA10)	0.025	0.024	0.025	0.025	0.025	0.026	0.027
Metronidazole (P01AB01)	0.011	0.011	0.012	0.012	0.013	0.014	0.014
Spiramycin (J01FA02)	0.009	0.008	0.007	0.007	0.006	0.006	0.005
Cefuroxime (J01DC02)	0.005	0.005	0.005	0.005	0.006	0.005	0.005
Nitrofurantoin (J01XE01)	0.002	0.002	0.003	0.003	0.003	0.003	0.003
Phenoxymethylpenicillin (J01CE02)	<0.0001	0.0001	0.0001	0.0001	0.0001	0.0001	0.0001
Other	0.026	0.023	0.022	0.022	0.021	0.017	0.013
Antibacterials for systemic use (J01)	1.512	1.527	1.531	1.584	1.573	1.609	1.607
Antiprotozoals (P01AB)	0.011	0.011	0.012	0.013	0.013	0.014	0.014
Total	1.523	1.538	1.543	1.597	1.586	1.623	1.621

Antimicrobial group	DDD/Prescriber
Antibacterials for systemic use (J01)	852	868	867	893	872	875	869
Antiprotozoals (P01AB)	6.2	6.4	6.7	7.0	7.4	7.8	7.7

^*Calculated as DID(J01CA04) divided by DID(J01CR02).

DDD, defined daily dose; DID, DDDs per 1,000 inhabitants per day.