Table 2.

Results for whole-mouth gingivitis efficacy endpoints at baseline and week 8

	Baseline mean (SD)*	Adjusted mean (SE) change from baseline†	Percent treatment difference relative to sonic‡	2-Sided P-value
MGI score
Sonic brush	2.113 (0.087)	0.269 (0.0184)	–	<0.001
Novel O-R brush	2.128 (0.116)	0.437 (0.0184)	62.5%
GBI score
Sonic brush	0.226 (0.128)	0.115 (0.0069)	–	<0.001
Novel O-R brush	0.246 (0.167)	0.174 (0.0069)	51.3%
Number of bleeding sites
Sonic brush	32.2 (15.26)	14.8 (0.78)	–	<0.001
Novel O-R brush	33.4 (17.67)	23.6 (0.77)	59.5%

^*Baseline gingivitis measures did not differ significantly (P ≥ 0.497) between treatment groups.

^†Reductions versus baseline were statistically significant for all measures for both brushes (P < 0.001).

^‡Percent treatment difference relative to sonic = 100 * (novel O-R – sonic)/sonic.