Table 3.
Results for whole-mouth plaque efficacy endpoints at baseline and week 8
| Baseline mean (SD)* | Adjusted mean (SE) change from baseline† | Percent treatment difference relative to sonic‡ | 2-Sided P-value | |
|---|---|---|---|---|
| Whole-mouth RMNPI | ||||
| Sonic brush | 0.607 (0.039) | 0.123 (0.0073) | – | <0.001 |
| Novel O-R brush | 0.603 (0.043) | 0.158 (0.0073) | 28.5% | |
| Gingival margin RMNPI | ||||
| Sonic brush | 1.000 (0.001) | 0.039 (0.0053) | – | 0.011 |
| Novel O-R brush | 0.999 (0.003) | 0.058 (0.0053) | 48.7% | |
| Proximal region RMNPI | ||||
| Sonic brush | 0.976 (0.049) | 0.324 (0.0234) | – | <0.001 |
| Novel O-R brush | 0.990 (0.031) | 0.458 (0.0234) | 41.4% |
*
Baseline plaque measures did not differ significantly (P ≥ 0.130) between treatment groups.
†
Reductions versus baseline were statistically significant for all measures for both brushes (P < 0.001).
‡
Percent treatment difference relative to sonic = 100 * (novel O-R – sonic)/sonic.