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. 2022 Aug 2;12:801300. doi: 10.3389/fonc.2022.801300

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Copyright © 2022 Chen, Hsu, Hsu, Tseng, Liu, Weng, Lin, Pan, Chen and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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NSCLC cell invasion was negatively correlated with Id2 expression. (A) Id2 mRNA expression levels in a cell line model of LADC (microarray analysis, left panel). CL1-5 cells exhibited greater invasive abilities than did CL1-0 cells (right panel). (B) Id2 mRNA expression evaluated through qRT-PCR and (C) protein levels evaluated in Western blot analysis in different NSCLC cells. Real-time RT-PCR assays used TATA-binding protein as an internal control. All experiments were executed in triplicate. Loading control in Western blots: GAPDH.