Table 1.

Tumor mutation characteristics by fluid type.

Variant statistic	Tumor, n = 34	BAL cfDNA, n = 31	Plasma, n = 34
Tumor variants detecteda	34 (100%)	25 (81%)	16 (47%)
Mean number of variants	5.1	1.9	0.91
Median number of variants	3.5	1.0	0.0
Mean VAF%	12.9	6.6	2.5
Median VAF%	4.2	2.4	0.09
Mean VAF%, drivers only	17.4	9.0	3.3
Median VAF%, drivers only	8.9	2.4	0.08

^aIncluding indels, see Supplementary Table S5; P < 0.05 level using a Monte-Carlo approach described in Materials and Methods.