Figure 7.

Genomic variation in high- and low-risk groups. (A) Scatter and Boxplot for all mutation counts (r=0.35, p=1.4e-15); (B) Scatter and Boxplot for non-synonymous mutation counts (r=0.35, p=3.8e-15); (C) Scatter and Boxplot for synonymous mutation counts (r=0.34, p=5.5e-15); (D-E) Waterfall plots for the mutations in 31 genes in high- (Left) and low-risk (Right) groups; (F) Forest map showing the 23 gene mutations of the highest frequency in high- and low-risk groups. Higher mutation frequencies were demonstrated in the high-risk group (*p < 0.05; **p < 0.01; ***p < 0.001); (G) Heatmap showing the colinearity of mutations in the 23 genes in high- and low-risk groups.