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. 2022 Jul 18;18(13):4901–4913. doi: 10.7150/ijbs.72318

Table 5.

Correlation between the studied biomarkers and the other measured laboratory parameters in COVID-19 patients' groups.

Severe COVID-19 Group
NEAT1 Expression TUG1 Expression CCL2 Expression TNF -α Expression IL-6 Expression
r P-value r P-value r P-value r P-value r P-value
Age 0.25 0.15 0.01 0.96 0.20 0.24 -0.23 0.18 -0.29 0.09
Oxygen -0.11 0.53 0.17 0.35 -0.21 0.22 -0.35 0.04 -0.16 0.37
Ferritin 0.18 0.30 0.33 0.05 0.03 0.87 0.47 0.005 0.17 0.32
CRP 0.02 0.92 0.37 0.03 0.31 0.07 0.19 0.27 0.08 0.32
D -dimer 0.24 0.17 0.28 0.10 0.53 0.001 0.35 0.04 0.32 0.06
TLC -0.54 0.001 -0.21 0.22 -0.35 0.04 -0.24 0.16 0.06 0.75
Hb 0.09 0.63 -0.08 0.65 -0.63 <0.001 -0.09 0.61 0.02 0.90
Absolute lymphocytes -0.15 0.39 0.002 0.99 -0.14 0.41 -0.42 0.01 0.12 0.48
NEAT1 Expression --- ----- 0.60 <0.001 0.39 0.02 0.13 0.46 0.06 0.73
TUG1 Expression 0.60 <0.001 ---- ----- 0.28 0.11 0.30 0.09 0.30 0.09
CCL2 Expression 0.39 <0.02 0.28 0.11 ---- ----- 0.41 0.01 0.53 0.001
TNF-α Expression 0.13 0.46 0.30 0.09 0.41 0.01 ---- ----- 0.60 <0.001
IL-6 Expression 0.06 0.73 0.30 0.08 0.53 0.001 0.60 <0.001 ---- -----
Moderate COVID-19 Group
NEAT1 Expression TUG1 Expression CCL2 Expression TNF- α Expression IL-6 Expression
r P-value r P-value R P-value r P-value r P-value
Age 0.32 0.03 0.17 0.28 0.08 0.59 0.09 0.58 -0.22 0.045
Oxygen -0.51 <0.001 -0.30 0.04 -0.36 0.02 -0.23 0.12 -0.69 <0.001
Ferritin 0.10 0.52 0.12 0.45 0.21 0.17 0.03 0.84 0.44 <0.001
CRP 0.04 0.80 0.28 0.06 0.40 0.006 0.24 0.12 0.60 <0.001
D -dimer 0.08 0.62 0.057 0.71 0.06 0.68 0.11 0.46 0.61 <0.001
TLC 0.16 0.29 0.19 0.20 0.15 0.31 0.02 0.92 0.06 0.60
Hb 0.10 0.51 -0.47 0.001 -0.47 0.001 -0.37 0.01 0.11 0.32
Absolute lymphocytes -0.27 0.07 -0.27 0.07 -0.32 0.03 -0.13 0.38 0.16 0.17
NEAT1 Expression ---- --- 0.57 <0.001 0.63 <0.001 0.38 0.01 0.52 <0.001
TUG1 Expression 0.57 <0.001 ---- --- 0.94 <0.001 0.65 <0.001 -0.05 0.76
CCL2 Expression 0.63 <0.001 0.94 <0.001 ---- --- 0.72 <0.001 0.06 0.72
TNF-α Expression 0.38 0.01 0.65 <0.001 0.72 <0.001 ---- --- -0.15 0.34
IL-6 Expression 0.52 <0.001 0.05 0.76 0.06 0.72 0.15 0.34 ---- ---