Table 2.

Phase separation related databases

Name	URL	Functions
IUPred	https://iupred2a.elte.hu/plot	Prediction of disordered protein regions
PLAAC	http://plaac.wi.mit.edu/	Prediction of prion-like region
PONDR	http://www.pondr.com	Predictor of natural disordered regions
MobiDB	https://mobidb.org	Provides information about intrinsically disordered regions and related features
CIDER	http://pappulab.wustl.edu/CIDER/	Calculation of many different parameters associated with disordered protein sequences
ZipperDB	https://services.mbi.ucla.edu/zipperdb/	Predictions of fibril-forming segments within protein
D2P2	http://d2p2.pro/	Database of disordered protein predictions
Metadisorder	http://iimcb.genesilico.pl/metadisorder/	Prediction of protein disorder
Expasy	https://web.expasy.org/compute_pi/	Computation of the theoretical pI (isoelectric point) and Mw (molecular weight)
AMYCO	http://bioinf.uab.es/amycov04/	Evaluation of mutation impact on prion-like proteins aggregation propensity
RPS	http://rps.renlab.org/#/Home	A comprehensive database of RNAs involved in liquid-liquid phase separation
RNAPhaSep	http://www.rnaphasep.cn/#/Home	A resource of RNAs undergoing phase separation
LLPSDB	http://biocomp.ucas.ac.cn/llpsdb/home.aspx	A database of proteins undergoing liquid-liquid phase separation in vitro