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. 2022 Aug 11;12(8):e054100. doi: 10.1136/bmjopen-2021-054100

Figure 1.

Figure 1

Study outline. included patients undergo a 7-week programme of washout of pre-existing antiglycemic treatment (except metformin) and run-in of empagliflozin. Hereafter, they are randomised to treatment for 5±1 weeks, followed by 3±1 weeks washout and crossover to 5±1 weeks treatment with the remaining study drug. Tests performed at each visit are summarised in tables 3 and 4. *See table 2 for screening procedure. **See tables 3 and 4 for visit overview. NPH, Neutral Protamine Hagedorn.