Table 1.
Comparative performance of the CRISPR-Cas12a-based assay for SARS-CoV-2 detection between self-collected saliva and nasopharyngeal swab.
| Parameters | CRISPR-Cas12a-based assay for SARS-CoV-2 detection | |
|---|---|---|
| Self-collected saliva (this study) | NP swab 6 | |
| Total samples tested | 578 | 164 |
| True-positive | 59 | 51 |
| True-negative | 501 | 111 |
| False-positive | 10 | 0 |
| False-negative | 8 | 2 |
| Sensitivity | 88.06% | 96.23% |
| Specificity | 98.04% | 100.00% |
| Positive predictive value (PPV) | 85.51% | 100.00% |
| Negative predictive value (NPV) | 98.43% | 98.23% |
| Diagnostic accuracy | 96.89% | 98.78% |
CRISPR: clustered regularly interspaced short palindromic repeats; SARS-CoV-2: severe acute respiratory syndrome coronavirus 2; NP: nasopharyngeal.