. 2022 Aug 6;22:100481. doi: 10.1016/j.lanepe.2022.100481

Table 4.

Performances of the Kawanet, abnormal initial echocardiography and modified-Kawanet score among different cohorts, ethnicities and patient characteristics, N=363.

Cohort	Score	Need for second-line treatment
		AUC	Sensitivity	Specificity
Italian cohort, N=177	Kawanet score^a (NA=23)	0.55	30%	76%
	Abnormal initial echocardiography^b (NA=4)	0.68	65%	70%
	Kawanet score + abnormal initial echocardiography^a^,^b (NA=27)	0.72	80%	53%
French cohort, N=186	Kawanet score^a	0.62	52%	69%
	Abnormal initial echocardiography^b	0.68	48%	87%
	Kawanet score + abnormal initial echocardiography^a^,^b	0.70	74%	55%
European ethnicity, N=183	Kawanet score^a (NA=17)	0.60	36%	78%
	Abnormal initial echocardiography^b (NA=4)	0.69	64%	74%
	Kawanet score + abnormal initial echocardiography^a^,^b (NA=21)	0.73	80%	56%
African/Afro-Caribbean ethnicity, N=110	Kawanet score^a (NA=2)	0.60	53%	66%
	Abnormal initial echocardiography^b	0.66	47%	86%
	Kawanet score + abnormal initial echocardiography^a^,^b (NA=2)	0.65	65%	51%
Asian ethnicity, N=37	Kawanet score^a	0.69	75%	67%
	Abnormal initial echocardiography^b	0.70	50%	90%
	Kawanet score + abnormal initial echocardiography^a^,^b	0.85	100%	61%
Complete KD, n=227	Kawanet score^a (NA=13)	0.58	44%	67%
	Abnormal initial echocardiography^b (NA=4)	0.66	47%	84%
	Kawanet score + abnormal initial echocardiography^a^,^b (NA=17)	0.70	76%	49%
Incomplete KD, n=136	Kawanet score^a (NA=10)	0.62	41%	80%
	Abnormal initial echocardiography^b	0.72	71%	73%
	Kawanet score + abnormal initial echocardiography^a^,^b (NA=10)	0.71	88%	47%
Male, n=222	Kawanet score^a (NA=12)	0.54	42%	68%
	Abnormal initial echocardiography^b (NA=2)	0.70	61%	79%
	Kawanet score + abnormal initial echocardiography^a^,^b (NA=14)	0.67	78%	47%
Female, n=141	Kawanet score^a (NA=11)	0.70	47%	77%
	Abnormal initial echocardiography^b (NA=2)	0.60	40%	81%
	Kawanet score + abnormal initial echocardiography^a^,^b (NA=13)	0.78	87%	51%
age <4 years, n=291	Kawanet score^a (NA=17)	0.59	39%	77%
	Abnormal initial echocardiography^b (NA=2)	0.71	63%	79%
	Kawanet score + abnormal initial echocardiography^a^,^b (NA=19)	0.71	79%	52%
age ≥4 years, n=72	Kawanet score^a (NA=6)	0.56	54%	50%
	Abnormal initial echocardiography^b (NA=2)	0.57	31%	83%
	Kawanet score + abnormal initial echocardiography^a^,^b (NA=8)	0.67	85%	33%

With a threshold ≥ 2.

Defined as initial coronary dilatation, aneurysm, pericarditis, myocarditis, or ventricular dysfunction. Kawanet score: 1 point per variable. Modified Kawanet score 2: 1 point per variable for the Kawanet score, 2 points for the initial echocardiography.