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. 2022 Jan 24;3(4):CASE21630. doi: 10.3171/CASE21630

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FIG. 2. — A: The biopsies showed a high-grade glial tumor that exhibited a variety of cell patterns. These included anaplastic glial cells with marked nuclear atypia and pleomorphism and cell shapes that varied from small rounded to giant multinucleated (hematoxylin-eosin [H&E], original magnification ×200). B: Multiple foci of necrosis (lower half of the field) are evident (H&E, original magnification ×200). C: Glial fibrillary acidic protein (GFAP) confirms the glial nature of the tumor (GFAP, original magnification ×200).