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. 2020 Aug 18;2:100016. doi: 10.1016/j.sleepx.2020.100016

Table 4.

HR with 95% CI of death by suicide among subjects with different combinations of depression and nightmares, compared to subjects without a diagnosis of depression who never or seldom experience nightmares, overall and stratified by gender.

Depression diagnosis Nightmares N Person years Deaths (%) P value for mortality rate difference HR (95% CI)a HR (95% CI)b
No Never/seldom 31,643 603,205 32 (0.1) 0.94 1.0 (reference) 1.0 (reference)
No Sometimes/often/always 7243 136,370 7 (0.1) 1.16 (0.51–2.64) 1.00 (0.44–2.28)
Yes Never/seldom 1356 25,184 20 (1.5) 0.97 16.5 (9.39–28.9) 12.3 (5.55–27.2)
Yes Sometimes/often/always 660 12,398 10 (1.5) 20.2 (9.83–41.3) 13.2 (7.25–24.1)
Women
No Never/seldom 19,585 381,273 9 (0.05) 0.78 1.0 (reference) 1.0 (reference)
No Sometimes/often/always 5263 102,010 3 (0.06) 1.27 (0.34–4.70) 1.08 (0.29–4.04)
Yes Never/seldom 936 17,819 8 (0.85) 0.94 19.1 (7.36–49.7) 15.2 (5.67–40.5)
Yes Sometimes/often/always 517 9910 5 (0.97) 22.0 (7.35–66.1) 13.3 (4.05–43.5)
Men
No Never/seldom 12,058 221,932 23 (0.19) 0.85 1.0 (reference) 1.0 (reference)
No Sometimes/often/always 1980 34,360 4 (0.20) 1.11 (0.38–3.20) 0.96 (0.33–2.79)
Yes Never/seldom 420 7365 12 (2.8) 0.73 15.3 (7.58–30.7) 12.6 (6.08–26.0)
Yes Sometimes/often/always 143 2488 5 (3.5) 19.4 (7.35–51.0) 12.6 (4.45–35.9)

We used the test-based method to calculate p values.

a

Adjusted for gender when appropriate.

b

Adjusted for gender when appropriate, occupational status, educational status, smoking, sleep duration, hypnotic use, cardiovascular disease, anxiety disorders, and psychotic disorders. Significant HRs are in bold.