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. 2022 Aug 1;11:e62. doi: 10.1017/jns.2022.52

Table 3.

Associations of soy isoflavones intake with osteoporotic fracture by any bone fracture history among postmenopausal women

Adj. HR (95 % CI)a P for interactionb
Overall With BF history Without BF history
Soy isoflavone intake (mg/d)
<18⋅7 1⋅00 (ref.) 1⋅00 (ref.) 1⋅00 (ref)
18⋅7–29⋅0 1⋅08 (0⋅95–1⋅22) 1⋅07 (0⋅87–1⋅31) 1⋅08 (0⋅92–1⋅27) 0⋅002
29⋅1–42⋅0 1⋅02 (0⋅89–1⋅16) 0⋅84 (0⋅67–1⋅05) 1⋅13 (0⋅95–.34)
>42⋅0 1⋅01 (0⋅86–1⋅18) 0⋅72 (0⋅55–0⋅93) 1⋅22 (1⋅01–1⋅48)
Daidzein intake (mg/d)
<7⋅7 1⋅00 (ref.) 1⋅00 (ref.) 1⋅00 (ref.)
7⋅7–12⋅0 1⋅06 (0⋅93–1⋅20) 1⋅05 (0⋅86–1⋅29) 1⋅07 (0⋅91–1⋅25) 0⋅004
12⋅17⋅6 1⋅00 (0⋅87–1⋅14) 0⋅83 (0⋅66–1⋅04) 1⋅11 (0⋅93–1⋅31)
>17⋅6 1⋅02 (0⋅88–1⋅19) 0⋅75 (0⋅58–0⋅97) 1⋅21 (1⋅00–1⋅47)
Genistein intake (mg/d)
<10⋅6 1⋅00 (ref.) 1⋅00 (ref.) 1⋅00 (ref.)
10⋅6–16⋅6 1⋅05 (0⋅92–1⋅19) 1⋅03 (0⋅84–1⋅27) 1⋅06 (0⋅90–1⋅24) 0⋅004
16⋅7–24⋅2 1⋅00 (0⋅88–1⋅15) 0⋅83 (0⋅67–1⋅04) 1⋅11 (0⋅94–1⋅31)
>24⋅2 1⋅03 (0⋅89–1⋅20) 0⋅76 (0⋅59–0⋅98) 1⋅22 (1⋅01–1⋅48)
Glycitein intake (mg/d)
<1⋅6 1⋅00 (ref.) 1⋅00 (ref.) 1⋅00 (ref.)
1⋅6–2⋅4 1⋅11 (0⋅98–1⋅25) 1⋅05 (0⋅86–1⋅29) 1⋅14 (0⋅97–1⋅34) 0⋅02
2⋅5–3⋅4 1⋅03 (0⋅90–1⋅19) 0⋅89 (0⋅71–1⋅12) 1⋅12 (0⋅95–1⋅34)
>3⋅4 1⋅03 (0⋅87–1⋅21) 0⋅77 (0⋅59–1⋅01) 1⋅21 (0⋅99–1⋅49)
a

Adjusting for: Age, BF history, income, educational level, cigarette smoking status, alcohol consumption, regular exercise, BMI, Charlson's Score, breasting time, calcium supplement use, daily dietary intake of calories, vitamin D, calcium and magnesium.

b

P-value for interaction between soy isoflavones and BF history.