High frequency electrical stimulation of fornix elicits currents in CRF + neurons in the PVN.
a) Electrically evoked EPSCs (−60 mV) and IPSCs (0 mV) recorded in CRF + neuron in the PVN in response to stimulation of the fornix at 20Hz for 1 s, repeated 10 times. b) There was a comparable ∼50% decrease in both EPSC and IPSC conductance over the duration of the stimulus train. c) Similarly, there was a comparable ∼50% decrease in the probability that a given stimulus elicited an EPSC or IPSC over the duration of the 20Hz stimulus trains.