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. Author manuscript; available in PMC: 2022 Oct 1.
Published in final edited form as: Neurogastroenterol Motil. 2021 Mar 15;33(10):e14118. doi: 10.1111/nmo.14118

TABLE 2.

Quality indicators determined to have low validity by consensus opinion from 17 experts using two-round Delphi technique.

Quality Indicator Agreement (%)
Importance Scientific Acceptability Usability Feasibility
IF manometry findings are equivocal, THEN esophagogram should be used to assess EGJ morphology and assess esophageal emptying. 41.2 41.2 41.2 41.2
IF the diagnosis of achalasia is made, THEN the Eckardt score should be documented to help measure symptom severity and response to treatment. 11.8 11.8 35.3 52.9
IF a patient is diagnosed with achalasia, THEN treatment with hydraulic dilation (ie, EsoFLIP™) is reasonable. 33.3 26.7 21.4 7.1
IF a patient is treated for a diagnosis of achalasia, THEN symptom improvement should be monitored by Eckardt score. 13.3 20.0 26.7 40.0
IF symptoms due to achalasia return after achalasia treatment with confirmed achalasia on objective testing, THEN patients are still a candidate for re-treatment with the same or different modality. 57.1 42.9 42.9 64.3
IF manometry confirms achalasia, THEN a timed barium esophagogram should be pursued to provide objective measure in the evaluation of treatment response. 50.0 31.3 43.8 50.0
IF a patient is diagnosed with achalasia, THEN pseudoachalasia should be first excluded. 50.0 50.0 50.0 43.8
IF a patient is presenting with dysphagia and the diagnosis is unclear for achalasia, THEN a trial of Botox or EndoFLIP technology, if available, can be used for diagnostic purposes. 43.8 25.0 31.3 31.3
IF a patient undergoes treatment for achalasia, THEN they should be counseled on the chronic nature of the disease and potential risk of progression to end-stage esophagus despite control of symptoms. 75.0 68.8 68.8 68.8
IF a patient is diagnosed with end-stage achalasia, THEN esophagectomy or percutaneous endoscopic gastrostomy (PEG) should be discussed as a treatment option. 56.3 43.8 68.8 56.3
IF a patient undergoes achalasia treatment and develops classic GERD symptoms, THEN the patient should be empirically treated with a proton pump inhibitor (PPI). 62.5 56.3 68.8 81.3
IF a patient has treated or untreated achalasia, THEN documentation should include counseling on the potential increased relative risk of squamous cell carcinoma. 43.8 31.3 31.3 37.5
IF a high-risk patient has treated or untreated achalasia, THEN they should undergo squamous cell carcinoma surveillance. 25.0 12.5 12.5 25.0
IF surveillance for squamous cell carcinoma in achalasia is started in high-risk patients with treated or untreated achalasia, THEN surveillance should extend in duration as long as the benefits of EGD outweigh the risk. 43.8 31.3 31.3 31.3