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Diagram of the ANKLE2 protein and identified variants. Diagram of the ANKLE2 protein with the most important functional domains and the identified ANKLE2 variants in this manuscript. ANK, ankyrin repeats; Cauli‐VI, Caulimovirus viroplasmin VI domain; LEM, Lap2, Emerin, MAN1 domain; TMD, transmembrane domain. [Colour figure can be viewed at wileyonlinelibrary.com]
