Table 1.
Baseline characteristics of participants (n = 248)
| Baseline characteristics | Nicotine replacement therapy (NRT), n = 82 | Nicotine-containing e-cigarettes, n = 84 | Nicotine-free e-cigarettes, n = 82 |
|---|---|---|---|
| Sex, %male | 44% | 55% | 50% |
| Age, mean years (SD) | 44 (13) | 44 (14) | 44 (13) |
| BMI, Mean (SD) | 26.5 (5.1) | 27.5 (5.9) | 27.4 (5.4) |
| Systolic blood pressure, mmHg (SD) | 132 (17) | 132 (18) | 131 (18) |
| Diastolic blood pressure, mmHg (SD) | 81 (12) | 83 (12) | 82 (14) |
| MAP, mean mm Hg (SD) | 98 (11) | 98 (11) | 97 (12) |
| Smoking tears, mean (SD) | 25(13) | 24 (13) | 25 (13) |
| Cigarettes per day, mean (SD) | 18 (7) | 18 (7) | 16 (7) |
| Smoking pack years, mean (SD) | 24 (19) | 23 (17) | 22 (17) |
| Exhaled air carbon monoxide (CO), mean parts per million (SD) | 16.9 (6.9) | 15.2 (7.9) | 14.3 (8.1) |
| Physical activity, mean weekly MET minutes (SD) | 2756 (2627) | 2772 (2669) | 3082 (3191) |
| %FMD, mean (SD) | 6.7 (4.0) | 6.2 (4.4) | 5.6 (3.6) |
| Artery diameter (pre-inflation), mean (SD) | 4.22 (0.66) | 4.13 (0.65) | 4.10 (0.56) |
| Artery diameter (post-inflation), mean (SD) | 4.47 (0.64) | 4.34 (0.61) | 4.36 (0.55) |
| Peak CVC for ACh, mean PU/mmHg (SD) | 1.34 (1.00) | 1.48 (1.02) | 1.49 (0.98) |
| Peak CVC for SNP, mean PU/mmHg (SD) | 1.35 (0.98) | 1.45 (1.02) | 1.15 (0.72) |
| Total cholesterol, mmol/l (SD) | 4.4 (1.0) | 4.5 (1.1) | 4.7 (1.2) |
| Total cholesterol/HDL ratio (SD) | 4.4 (1.9) | 4.1 (1.7) | 4.1 (1.9) |
| FTND, points (SD) | 6 (2) | 6 (2) | 6 (2) |
| Q-Risk, % (SD) | 7.5 (8.7) | 8.6 (10) | 7.8 (9.1) |
| Q-Risk – Heart Health, years (SD) | 53 (16) | 54 (16) | 54 (15) |
ACh, acetylcholine; BMI, body mass index; CVC, peak cutaneous vascular conductance; %FMD, percentage change in flow-mediated dilation; FTND, Fagerstrom Test for Nicotine Dependence; HDL, high-density lipoprotein; MAP, mean arterial pressure; MET, metabolic equivalent; SNP, sodium nitroprusside