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. 2022 Aug 16;20:276. doi: 10.1186/s12916-022-02451-9

Table 2.

Results of model estimating change in % flow-mediated dilation, cutaneous vascular conductance in response to acetylcholine and to sodium nitroprusside, and mean arterial pressure at 3 and 6 months follow-up: all participants

Variables Group/follow-up B-coeff Exp (B) 95% CI p value
Lower Upper
%FMD
Group NRT over nicotine-containing e-cigarettes 0.43 1.56 − 0.64 1.50 0.43
Nicotine-free e-cigarettes over nicotine-containing e-cigarettes − 0.59 0.56 − 1.76 0.59 0.33
Follow-up 3 m over baseline 3.33 27.90 2.61 4.05 0.001
6 m over baseline 2.69 14.67 2.02 3.35 0.001
Gender Male over female − 1.32 0.27 − 2.24 − 0.40 0.005
Age − 0.02 0.98 − 0.05 0.01 0.23
Intercept 9.89 8.29 11.5 0.001
Peak CVC for Ach
Group NRT over nicotine-containing e-cigarettes − 0.03 0.97 − 0.26 0.20 0.80
Nicotine-free e-cigarettes over nicotine-containing e-cigarettes − 0.01 0.99 − 0.25 0.23 0.93
Follow-up 3 m over baseline 0.20 1.27 0.01 0.40 0.04
6 m over baseline 0.27 1.31 0.09 0.45 0.004
Gender Male over female − 0.02 0.99 − 0.21 0.18 0.88
Age − 0.01 0.99 0.994 0.01 0.17
Intercept 1.79 1.36 2.23 0.001
Peak CVC for SNP
Group NRT over nicotine-containing e-cigarettes − 0.03 0.98 − 0.26 0.29 0.83
Nicotine-free e-cigarettes over nicotine-containing e-cigarettes − 0.14 0.87 − 0.37 0.09 0.23
Follow-up 3 m over baseline 0.26 1.52 0.10 0.42 0.001
6 m over baseline 0.28 1.57 0.11 0.45 0.002
Gender Male over female − 0.07 0.93 − 0.26 0.12 0.48
Age − 0.01 1.00 0.995 0.01 0.16
Intercept 1.63 1.23 2.03 0.001
MAP
Group NRT over nicotine-containing e-cigarettes − 1.51 0.22  − 4.24 1.23 0.28
Nicotine-free e-cigarettes over Nicotine-containing e-cigarettes 0.28 1.33  − 2.88 3.44 0.861
Follow-up 3 m over baseline − 1.74 0.18  − 2.57  − 0.91 0.001
6 m over baseline − 1.41 0.25  − 2.31  − 0.51 0.002
Gender Male over female 4.33 75.55 1.86 6.79 0.001
Age 0.23 1.26 1.15 1.39 0.001
Intercept 9.54 7.92 11.17 0.001

ACh, acetylcholine; CVC, peak cutaneous vascular conductance; %FMD, percentage change in flow-mediated dilation; MAP, mean arterial pressure; SNP, sodium nitroprusside