Table 2.
Results of model estimating change in % flow-mediated dilation, cutaneous vascular conductance in response to acetylcholine and to sodium nitroprusside, and mean arterial pressure at 3 and 6 months follow-up: all participants
Variables | Group/follow-up | B-coeff | Exp (B) | 95% CI | p value | |
---|---|---|---|---|---|---|
Lower | Upper | |||||
%FMD | ||||||
Group | NRT over nicotine-containing e-cigarettes | 0.43 | 1.56 | − 0.64 | 1.50 | 0.43 |
Nicotine-free e-cigarettes over nicotine-containing e-cigarettes | − 0.59 | 0.56 | − 1.76 | 0.59 | 0.33 | |
Follow-up | 3 m over baseline | 3.33 | 27.90 | 2.61 | 4.05 | 0.001 |
6 m over baseline | 2.69 | 14.67 | 2.02 | 3.35 | 0.001 | |
Gender | Male over female | − 1.32 | 0.27 | − 2.24 | − 0.40 | 0.005 |
Age | − 0.02 | 0.98 | − 0.05 | 0.01 | 0.23 | |
Intercept | 9.89 | 8.29 | 11.5 | 0.001 | ||
Peak CVC for Ach | ||||||
Group | NRT over nicotine-containing e-cigarettes | − 0.03 | 0.97 | − 0.26 | 0.20 | 0.80 |
Nicotine-free e-cigarettes over nicotine-containing e-cigarettes | − 0.01 | 0.99 | − 0.25 | 0.23 | 0.93 | |
Follow-up | 3 m over baseline | 0.20 | 1.27 | 0.01 | 0.40 | 0.04 |
6 m over baseline | 0.27 | 1.31 | 0.09 | 0.45 | 0.004 | |
Gender | Male over female | − 0.02 | 0.99 | − 0.21 | 0.18 | 0.88 |
Age | − 0.01 | 0.99 | 0.994 | 0.01 | 0.17 | |
Intercept | 1.79 | 1.36 | 2.23 | 0.001 | ||
Peak CVC for SNP | ||||||
Group | NRT over nicotine-containing e-cigarettes | − 0.03 | 0.98 | − 0.26 | 0.29 | 0.83 |
Nicotine-free e-cigarettes over nicotine-containing e-cigarettes | − 0.14 | 0.87 | − 0.37 | 0.09 | 0.23 | |
Follow-up | 3 m over baseline | 0.26 | 1.52 | 0.10 | 0.42 | 0.001 |
6 m over baseline | 0.28 | 1.57 | 0.11 | 0.45 | 0.002 | |
Gender | Male over female | − 0.07 | 0.93 | − 0.26 | 0.12 | 0.48 |
Age | − 0.01 | 1.00 | 0.995 | 0.01 | 0.16 | |
Intercept | 1.63 | 1.23 | 2.03 | 0.001 | ||
MAP | ||||||
Group | NRT over nicotine-containing e-cigarettes | − 1.51 | 0.22 | − 4.24 | 1.23 | 0.28 |
Nicotine-free e-cigarettes over Nicotine-containing e-cigarettes | 0.28 | 1.33 | − 2.88 | 3.44 | 0.861 | |
Follow-up | 3 m over baseline | − 1.74 | 0.18 | − 2.57 | − 0.91 | 0.001 |
6 m over baseline | − 1.41 | 0.25 | − 2.31 | − 0.51 | 0.002 | |
Gender | Male over female | 4.33 | 75.55 | 1.86 | 6.79 | 0.001 |
Age | 0.23 | 1.26 | 1.15 | 1.39 | 0.001 | |
Intercept | 9.54 | 7.92 | 11.17 | 0.001 |
ACh, acetylcholine; CVC, peak cutaneous vascular conductance; %FMD, percentage change in flow-mediated dilation; MAP, mean arterial pressure; SNP, sodium nitroprusside