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. 2022 Aug 16;22:221. doi: 10.1186/s12906-022-03702-1

Table 2.

The effects of E. globulus leaf solvent fractions against P. berghei infected mice in the 4-day suppressive test

Treatments % Parasitemia % Parasitemia suppression Mean survival time (day)
2%tween 80 (10 ml/kg) 34.67 ± 2.16 9.50 ± 0.99
CQ (25 mg/kg) 0.00 ± 0.00 100.00 ± 0.00a3 29.50 ± 0.34a3
CF (mg/kg) 100 17.00 ± 0.89 52.91 ± 3.43a3b3 16.83 ± 0.95 a3b3
 200 12.33 ± 0.67 66.08 ± 1.58a3b3 17.17 ± 0.48a3b3
 400 11.00 ± 0.93 69.93 ± 2.01a3b3 19.00 ± 1.06a3b3
EAF (mg/kg) 100 16.00 ± 0.97 53.71 ± 1.64a3b3 16.00 ± 0.73a3b3
 200 13.67 ± 0.71 60.31 ± 1.66a3b3 16.17 ± 1.01a3b3
 400 10.83 ± 0.79 68.13 ± 3.05a3b3 22.50 ± 0.92a3b3
DW (10 ml/kg) 36.50 ± 1.65 9.00 ± 0.73
CQ (25 mg/kg) 0.00 ± 0.00 100.00 ± 0.00a3 29.50 ± 0.34a3
AF (mg/kg) 100 26.17 ± 1.01 23.28 ± 5.05a3b3 10.33 ± 1.02 b3
 200 22.33 ± 0.95 34.01 ± 5.52a3b3 12.17 ± 0.75b3
 400 16.83 ± 0.91 50.61 ± 3.83a3b3 15.67 ± 0.67a3b3

Data are expressed as mean ± SEM

CF Chloroform fraction, EAF Ethyl acetate fraction, DW Distilled water, AF Aqueous fraction, CQ Chloroquine

1p < 0.05

2p < 0.01, p < 0.001

acompared to negative controls

bcompared to chloroquine